Common Diseases That Trigger Hives in Adults

Hives, medically known as urticaria, are an incredibly common skin condition that can affect people of all ages, including adults. Characterized by itchy, raised welts or bumps on the skin, hives can be a result of various triggers. While allergies and stress are often associated with hives, there’s a lesser-known aspect to this condition: the connection between hives and underlying diseases in adults. In this guide, we will explore the diseases that can trigger hives in adults and emphasize the importance of understanding these underlying health conditions.

Understanding Hives In Adults: A Brief Overview

Before we dive into the diseases associated with hives in adults, let’s grasp the basics of this skin condition. Hives typically manifest as red, swollen, and itchy welts on the skin, varying in size and shape. These hives can appear suddenly and may migrate to different areas of the body within hours. While hives can be acute (lasting for less than six weeks) or chronic (persisting for more than six weeks), our focus here is on chronic hives in adults, which often have an underlying medical cause.

Allergies: The Usual Suspects

One of the most well-known triggers for hives in adults is allergies. Allergic reactions to foods, medications, insect stings, or pollen can lead to the release of histamine, a chemical that causes blood vessels to leak. This leakage results in the characteristic redness, swelling, and itching of hives.

However, it’s essential to distinguish between acute and chronic hives. Acute hives, the most common type, are often linked to allergies and tend to resolve relatively quickly once the allergen is removed. Chronic hives, on the other hand, can persist for extended periods and are frequently associated with underlying health conditions.

Beyond Allergies: Diseases That Trigger Hives in Adults

1. Autoimmune Disorders

Autoimmune diseases occur when the immune system mistakenly attacks healthy cells and tissues in the body. Several autoimmune disorders have been linked to chronic hives in adults, including:

  • Thyroid Disorders: Conditions such as Hashimoto’s thyroiditis and Graves’ disease, which affect the thyroid gland, can lead to chronic hives. Thyroid hormones play a significant role in regulating the immune system, and their imbalance can trigger hives.
  • Lupus: Systemic lupus erythematosus (SLE) is an autoimmune disease that can cause a wide range of symptoms, including hives. The exact mechanism behind hives in lupus is complex and not entirely understood, but it underscores the interplay between autoimmune conditions and skin reactions.

2. Infections

Certain infections, including viral and bacterial, can be responsible for hives in adults. These infections may stimulate the immune system, leading to hives as a secondary reaction. One significant infection to consider is HIV (Human Immunodeficiency Virus).

– HIV and Hives

HIV, a virus that weakens the immune system, can sometimes manifest with skin symptoms, including hives. In adults, chronic hives can be an early sign of HIV infection. The virus can disrupt the immune system’s normal functioning, making the body more susceptible to various skin conditions, including hives. Recognizing the connection between HIV and hives is crucial, as it underscores the need for early detection and treatment.

The HIV Testing: A Lifeline for Health

When discussing the connection between HIV and hives in adults, it’s vital to highlight the importance of regular HIV testing. Early detection of HIV is critical for several reasons:

1. Early Treatment

Early detection allows individuals to initiate antiretroviral therapy (ART) promptly. ART can effectively suppress the virus, slow disease progression, and protect the immune system from further damage. This not only improves the individual’s overall health but also reduces the risk of developing skin conditions like chronic hives.

2. Preventing Transmission

Knowing one’s HIV status is essential for preventing the transmission of the virus to others. Individuals who are aware of their HIV-positive status can take steps to protect their sexual partners, reducing the risk of transmission.

In Jacksonville, Florida, Hope Across the Globe is dedicated to promoting HIV awareness and offering free HIV testing Jacksonville services to the community. Their commitment to early detection and education plays a crucial role in preventing the spread of HIV and its associated complications, including skin conditions like hives.

Stress: A Common Culprit

While diseases like autoimmune disorders and infections can trigger hives in adults, it’s essential to acknowledge the role of stress in this equation. Stress, both physical and emotional, can contribute to hives. The body’s response to stress includes the release of histamine, the same chemical involved in allergic reactions. This histamine release can lead to hives, even in the absence of an underlying disease.

Chronic stress, in particular, can increase the risk of chronic hives in adults. Managing stress through relaxation techniques, mindfulness, and stress-reduction strategies can help alleviate hives in some cases.

When to Seek Medical Help

If you’re experiencing chronic hives as an adult, it’s crucial to consult a healthcare professional. While hives can be uncomfortable and frustrating, they can also serve as a warning sign of an underlying health issue. A healthcare provider can perform a thorough evaluation, including a medical history review and diagnostic tests, to identify the root cause of your hives.

Remember that diagnosing the underlying disease is the key to effectively managing chronic hives. Once the root cause is identified and addressed, your healthcare provider can develop a tailored treatment plan to alleviate your symptoms and improve your overall health.


Hives in adults are not always the result of allergies or stress. They can also be a sign of underlying diseases, including autoimmune disorders and infections like HIV. Recognizing the connection between hives and these health conditions is essential for early detection and treatment.

In Jacksonville, Hope Across the Globe’s commitment to providing free HIV testing services highlights the significance of early detection in preventing complications like chronic hives. Whether your hives are due to allergies, stress, or an underlying disease, seeking medical help is crucial to finding relief and addressing the root cause of this skin condition. Don’t hesitate to consult a healthcare professional if you’re experiencing chronic hives or have concerns about your health.

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